low blood pressure and pulse; low blood pressure and pulse; viral gastritis//vomiting; Calf pain; This spontaneous case was reported by an other health care professional and describes the occurrence of HEART RATE DECREASED (low blood pressure and pulse), HYPOTENSION (low blood pressure and pulse) and GASTRITIS VIRAL (viral gastritis//vomiting) in a 79-year-old male patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. Previously administered products included for Product used for unknown indication: High dose flu vaccine (High dose) on 27-Dec-2024. Past adverse reactions to the above products included No adverse effect with High dose flu vaccine. On 15-Jan-2025, the patient received dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Intramuscular use) 1 dosage form. In January 2025, the patient experienced GASTRITIS VIRAL (viral gastritis//vomiting) (seriousness criterion hospitalization). On 16-Jan-2025, after starting mRNA-1273.712 (SPIKEVAX 2024-2025 PFS), the patient experienced PAIN IN EXTREMITY (Calf pain). On 18-Jan-2025, the patient experienced HEART RATE DECREASED (low blood pressure and pulse) (seriousness criterion hospitalization) and HYPOTENSION (low blood pressure and pulse) (seriousness criterion hospitalization). The patient was hospitalized on 18-Jan-2025 due to GASTRITIS VIRAL, HEART RATE DECREASED and HYPOTENSION. On 19-Jan-2025, HEART RATE DECREASED (low blood pressure and pulse) and HYPOTENSION (low blood pressure and pulse) was resolving. On 20-Jan-2025, PAIN IN EXTREMITY (Calf pain) had resolved. At the time of the report, GASTRITIS VIRAL (viral gastritis//vomiting) was resolving. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood pressure measurement: Low. On an unknown date, Culture: Negative. On an unknown date, Heart rate: Low. On an unknown date, Laboratory test: normal. For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Intramuscular use), the reporter did not provide any causality assessments. No concomitant medications were reported. On 18-Jan-2025, patient started vomiting and admitted to the hospital due to low blood pressure and pulse. Blood clots were ruled out. Vomiting stopped. Patient would be released from hospital on 21-Jan-2025. The final diagnosis was viral gastritis. No treatment medications were reported.; Reporter’s Comments: Company comment: Causality of event gastritis viral was assessed as not related due to lack of biological plausibility. The benefit-risk relationship of product is not affected by this report.