sore throat; fatigue; redness which had been climbing up my throat into my mouth; it looks more like a little bit more like a rash almost (the redness in my throat converted to a rash appearance).; This spontaneous case was reported by a patient and describes the occurrence of OROPHARYNGEAL PAIN (sore throat), ORAL MUCOSAL ERYTHEMA (redness which had been climbing up my throat into my mouth), ORAL MUCOSAL ERUPTION (it looks more like a little bit more like a rash almost (the redness in my throat converted to a rash appearance).) and FATIGUE (fatigue) in a 75-year-old male patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis. The patient’s past medical history included COVID-19 in July 2024. Previously administered products included for Product used for unknown indication: COVID-19 Vaccine (Patient received 6 shots since 2019) in September 2023. Past adverse reactions to the above products included No adverse effect with COVID-19 Vaccine. On 05-Jan-2025, the patient received seventh dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Intramuscular use) 1 dosage form. On 06-Jan-2025, the patient experienced OROPHARYNGEAL PAIN (sore throat) and FATIGUE (fatigue). In January 2025, the patient experienced ORAL MUCOSAL ERYTHEMA (redness which had been climbing up my throat into my mouth) and ORAL MUCOSAL ERUPTION (it looks more like a little bit more like a rash almost (the redness in my throat converted to a rash appearance).). At the time of the report, OROPHARYNGEAL PAIN (sore throat), ORAL MUCOSAL ERYTHEMA (redness which had been climbing up my throat into my mouth), ORAL MUCOSAL ERUPTION (it looks more like a little bit more like a rash almost (the redness in my throat converted to a rash appearance).) and FATIGUE (fatigue) had not resolved. For mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Intramuscular use), the reporter did not provide any causality assessments. Patient got the 1st two shots when they first came out. Then got the boosters. Then had over 4 boosters since. Patient did not receive vaccines within the past 4 weeks, and no medical conditions has reported. No concomitant medication was reported. On January 6th, at the end of the day, patient developed a sore throat and fatigue. It lasted longer than patient would have thought. Patient went to primary care doctor, and he gave me a swab for the throat to rule out Strep, it was not the strep. He said it could be a passing sore throat, which they could get, although it’s already been at that point 10 or 11 days. Or could be possibly associated with the vaccine. Patient waited another 6 days and the redness which had been climbing up the throat into mouth, his wife looked in and it looked more like a little bit like a rash almost (the redness in throat converted to a rash appearance). Patient made an appointment for Friday to see doctor again. Patient was concerned about, something that will spread or that was a rash. It was not like typical of a viral sore throat because it just didn’t go away, and it was not progressing and getting worse. It was just changing in nature. No treatment information was reported. This case was linked to US-MODERNATX, INC.-MOD-2025-781696 (E2B Linked Report).; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781696:Female case