Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. No treatment information was reported. This case contains information for patient 15 out of 32. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 1 (Master case); Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. No treatment information was reported. This case contains information for patient 29 out of 32. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 29; Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. Not Provided No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. No treatment information was reported. This case contains information for patient 2 out of 32. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 2; Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms or events. No treatment information was provided. This case is reported for patient 14 out of 32 patients. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 14; Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. No treatment information was reported. This case contains information for patient 23 out of 32. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 1 (Master case); Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms/events. No treatment information was reported. This case contains information for patient 13 out of 32. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 1 (Master case); Reported Cause(s) of Death: Death unexplained

Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby; This spontaneous case was reported by a patient family member or friend and describes the occurrence of DEATH (Caller said that 32 people of her family were killed because of the vaccine including her niece’s baby) in a patient of an unknown age and gender who received SPIKEVAX NOS (SPIKEVAX NOS) for COVID-19 prophylaxis. No Medical History information was reported. On an unknown date, the patient received dose of SPIKEVAX NOS (SPIKEVAX NOS) (Intramuscular use) 1 dosage form. Death occurred on an unknown date The cause of death was not reported. It is unknown if an autopsy was performed. No concomitant medication was reported. It was unknown if the patient experienced any additional symptoms or events. No treatment information was provided. This case is reported for patient 12 out of 32 patients. Company comment: This case involves a patient of unknown age and gender, with no reported medical history, who experienced the event death (reported as “32 people of her family were killed because of the vaccine”), which occurred on an unknown date, after receiving an unspecified dose of the COVID-19 vaccine (SPIKEVAX COVID-19 VACCINE NOS). The event latency could not be accurately assessed, as the exact dates of vaccination and death were not reported. The exact cause of death was not reported, and it is unknown if an autopsy was performed or not. No further clinical details were provided, such as patient’s demographics, medical history, current conditions, concomitant medications, diagnostic/laboratory tests, circumstances surrounding the event, event details, cause, and date of death. The benefit-risk relationship of product is not affected by this report. This case was linked to US-MODERNATX, INC.-MOD-2025-781803 (E2B Linked Report). Reporter did not allow further contact; Sender’s Comments: US-MODERNATX, INC.-MOD-2025-781803:Patient 12; Reported Cause(s) of Death: Death unexplained

Shingrix – Late second dose; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of drug dose administration interval too long in a 57-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis. Previously administered products included Shingrix (Patient received first dose in 2021). On 01-NOV-2024, the patient received the 2nd dose of Shingrix. On 01-NOV-2024, an unknown time after receiving Shingrix, the patient experienced drug dose administration interval too long (Verbatim: Shingrix – Late second dose). The outcome of the drug dose administration interval too long was unknown. Additional Information: GSK Receipt Date: 10-JAN-2025 Pharmacist mentioned that a patient received the first dose of Shingrix in 2021 and second dose was given on 01-NOV-2024. The pharmacist asked if the patient should receive a third dose. The reporter did not share information about Shingrix doses such as lot number and expiration date. The patient received 2nd dose of Shingrix, later than the recommended interval, which led to lengthening of vaccinations schedule.

COVID; COVID; This is a spontaneous report received from a Consumer or other non HCP, Program ID. A patient (age and gender not provided) received BNT162b2 (BNT162B2 NOS), as dose 1, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient’s relevant medical history included: “Small fiber neuropathy” (unspecified if ongoing); “adrenergic dysautonomia” (unspecified if ongoing); “POTS” (unspecified if ongoing); “ataxia” (unspecified if ongoing); “downbeating nystagmus” (unspecified if ongoing); “superventicular tachycardia” (unspecified if ongoing); “severe dysmotility issues” (unspecified if ongoing); “left atrial inflammation x4” (unspecified if ongoing); “ocular rosacea” (unspecified if ongoing); “blephiritis” (unspecified if ongoing); “polyneuropathy” (unspecified if ongoing); “immune deficiency” (unspecified if ongoing); “macrocytosis without anemia” (unspecified if ongoing); “elevated liver enzymes” (unspecified if ongoing), notes: gone; “gone-acute fatty liver- gone” (unspecified if ongoing), notes: gone; “Igg3 subclass deficiency” (unspecified if ongoing); “left arm swelled to wrist and halfway down back” (unspecified if ongoing); “Still hurts” (unspecified if ongoing); severe dysmotility issues; b cells tanking wbc. The patient’s concomitant medications were not reported. The following information was reported: DRUG INEFFECTIVE (medically significant), COVID-19 (medically significant), outcome “unknown” and all described as “COVID”. Clinical course: First shot. Not safe or effective. Still got Covid a year and a half later. The information on the batch/lot number for BNT162b2 will be requested and submitted if and when received.

extreme dizziness; can’t get out of bed; My head is almost never clear; This is a spontaneous report received from a Consumer or other non HCP, Program ID. An 84-year-old patient received BNT162b2 (BNT162B2), as dose number unknown, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient’s relevant medical history and concomitant medications were not reported. The following information was reported: DIZZINESS (hospitalization), outcome “not recovered”, described as “extreme dizziness”; BEDRIDDEN (non-serious), outcome “not recovered”, described as “can’t get out of bed”; BRAIN FOG (non-serious), outcome “unknown”, described as “My head is almost never clear”. The patient underwent the following laboratory tests and procedures: Test: all good. Clinical details: patient was 84 years old. Patient has been having extreme dizziness and was in the hospital. Tests were all good. His/her head was almost never clear. Sometimes he/she can’t get out of bed. Patient had the Pfizer shot at the beginning of COVID. Patient asked if this could be from the vaccine. The information on the batch/lot number for BNT162b2 will be requested and submitted if and when received.