Large local reaction at injection site, characterized by firm swelling >6 cm and mild erythema, no pain. Resolved with conservative care over 3 days. Refer to DHA IHD

no second dose was administered; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of incomplete course of vaccination in a patient who received HAB (Twinrix) for prophylaxis. Previously administered products included Twinrix (received 1st dose of Twinrix vaccine on March 2024). On an unknown date, the patient did not receive Twinrix. On an unknown date, an unknown time after receiving Twinrix, the patient experienced incomplete course of vaccination (Verbatim: no second dose was administered). The outcome of the incomplete course of vaccination was unknown. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK Receipt Date: 10-JAN-2025 The Healthcare professional reported on the day of reporting, 10th January 2025 that a patient received the first dose of Twinrix on March 2024 and had not received the second dose. The reporter was called to made clinical decision, no second dose was administered at the moment of the call yet. Till the time of reporting, the patient did not receive 2nd dose of Twinrix, which led to incomplete course of vaccination.

0.5mL of an adult Havrix dose to a 16 year old female patient; This non-serious case was reported by a other health professional via call center representative and described the occurrence of adult product administered to child in a 16-year-old female patient who received HAV (Havrix adult) (batch number 2345B, expiry date 02-FEB-2026) for prophylaxis. On 02-DEC-2024, the patient received the 2nd dose of Havrix adult. On 02-DEC-2024, an unknown time after receiving Havrix adult, the patient experienced adult product administered to child (Verbatim: 0.5mL of an adult Havrix dose to a 16 year old female patient). The outcome of the adult product administered to child was unknown. Additional Information: GSK receipt date: 08-JAN-2025 The physician reported that 0.5mL of an adult Havrix dose to a 16 year old female patient because they did not stock the pediatric formulation in the office, which led to adult product administered to child.

Inappropriate schedule of vaccine; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of incomplete course of vaccination in a adult female patient who received Herpes zoster (Shingrix) for prophylaxis. Previously administered products included Shingrix (first dose of Shingrix about 2.5 years ago). On an unknown date, the patient did not receive the 2nd dose of Shingrix. On an unknown date, an unknown time after receiving Shingrix, the patient experienced incomplete course of vaccination (Verbatim: Inappropriate schedule of vaccine). The outcome of the incomplete course of vaccination was unknown. Additional Information: GSK Receipt Date: 06-JAN-2025 Till the time of reporting the patient had not received the second dose of Shingrix, which led to incomplete course of vaccination. The reporter asked what were the recommendations as to if she should receive her second dose since it’s way outside of the 2 to 6 month window. The reporter consented to follow up.

received first dose of shingles vaccine January 18th 2024; This non-serious case was reported by a consumer via call center representative and described the occurrence of incomplete course of vaccination in a 55-year-old male patient who received Herpes zoster (Shingles vaccine) for prophylaxis. Previously administered products included Shingles vaccine (Patient received first dose on 18-JAN-2024). On an unknown date, the patient did not receive the 2nd dose of Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine, the patient experienced incomplete course of vaccination (Verbatim: received first dose of shingles vaccine January 18th 2024). The outcome of the incomplete course of vaccination was unknown. Additional Information: GSK Receipt Date: 03-JAN-2025 Patient received first dose of shingles vaccine brand, lot number and expiration date was unknown on January 18th 2024 and he forgot to get the second dose 6 months later. Till the time of reporting the patient did not receive second dose of Shingles vaccine which led to incomplete course of vaccination.

Suspected vaccination failure; the vaccination didn’t stop it for me; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis. On an unknown date, the patient received Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant) and shingles (Verbatim: the vaccination didn’t stop it for me). The outcome of the vaccination failure and shingles were not reported. It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingles vaccine. The company considered the vaccination failure and shingles to be unrelated to Shingles vaccine. Additional Information: GSK Receipt Date: 13-JAN-2025 This case was reported by a patient via interactive digital media. The patient reported that the vaccination did not stop it for him/her. This case was considered as suspected vaccination failure as details regarding completion of primary vaccination schedule, time to onset for shingles and laboratory confirmation regarding shingles were unknown at the time of reporting.; Sender’s Comments: Vaccination failure is a listed event which, due to the following criteria (insufficient information provided about the clinical description, details regarding the completion of primary vaccination schedule, time to onset and laboratory confirmation of disease) is considered unrelated to GSK Shingles vaccine. Herpes zoster is an unlisted event which is considered unrelated to GSK Shingles vaccine.

I got sick; This non-serious case was reported by a consumer via interactive digital media and described the occurrence of sickness in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis. On an unknown date, the patient received Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine, the patient experienced sickness (Verbatim: I got sick). The outcome of the sickness was not reported. It was unknown if the reporter considered the sickness to be related to Shingles vaccine. It was unknown if the company considered the sickness to be related to Shingles vaccine. Additional Information: GSK Receipt Date: 07-JAN-2025 This case was reported by a patient via interactive digital media. The patient got sick after his/her shingles shot but it was nothing compared to getting actual shingles.

caller unsure if patient received full amount of dose as some of the diluent leaked out due to the suction; syringe experienced suction when twisting the needle onto the hub of syringe causing cap; caller unsure if patient received full amount of dose as some of the diluent leaked out due to the suction; device fluid leak; no adverse event; This spontaneous report was received from registered nurse and refers to a 15-month-old. patient of unknown gender. The patient’s medical history was not reported. The patient’s concurrent conditions were not reported. Concomitant therapies were not reported. On an unknown date, the patient started therapy with measles, mumps, and rubella (wistar ra 27-3) virus vaccine, live (M-M-R II) injection, lot #Y010046, expiration date: 29-MAY-2026, administered for prophylaxis (strength, and route of administration were not provided), status albumin- rHA; and sterile diluent (BAXTER STERILE DILUENT) solution for injection/infusion, lot #1973242, expiration date: 17-FEB-2026 (strength, route of administration, and indication were not provided). On an unknown date, the sterile diluent syringe experienced suction when twisting the needle onto the hub of syringe causing cap of syringe to pop off. The nurse reported that a dose of M-M-R-II was administered to a patient that was reconstituted using the defective sterile diluent syringe and caller unsure if patient received full amount of dose as some of the diluent leaked out due to the suction. No adverse events reported.

About two months after vaccination patient completely lost ability to remember any new information. At that time we did not connect this with vaccination. On 12/12/2021 patient received Dose 3 of :Moderna (booster), lot 60H21A In early 2022 we started tests at clinic. MRI scans did not show any damage of patient’s brain. In May 2022 patient received wrong (as was shown later) diagnosis of Alzheimer, by Dr of clinic, and started treatment with Donepezil. In Summer 2023 Alzheimer diagnosis was excluded by lumbar puncture at clinic. MRI performed in Sep 2023 have shown about 40% reduction of gray matter volume. doctor gave diagnosis of CorticoBasal degeneration. At the end of 2023, analyzing my notes, I came to conclusion that patient’s memory was switched off in 2021 due to Moderna vaccination. In addition to brain atrophy, by 2023 patient also developed severe walking difficulties. The brain atrophy may be the result of wrong treatment with donepezil, while she did not have Alzheimer (there are several scientific papers that show that Donepezil accelerate neurodegeneration in people who do not have Alzheimer). Patient is now completely disables and required 24/7 caregiver support. In 2024 we have followed with clinical trial and study, and with 3-days detailed study at clinic. These studies did not add any more clarity to the reasons of patient’s conditions. The doctors at numerous clinics were informed about my conclusion that patient’s memory was switched off by mRNA vaccination, but neither deny no confirm this conclusion. I have also conveyed to clinic doctors that the fact that patient’s memory was switched off so fast makes patient a new “study Patient”* – a person with a known reason that affected her memory mechanism. Genetics, molecular, and other studies of patient may give answers to memory mechanisms questions – potentially bringing the Prize to successful researchers. Finding and synthesizing a suitable molecular substance that could switch memory back on – would bring a second Prize to courageous scientists. * Different study Patient – person whose hippocampus was surgically destroyed and he lost ability to remember new things – numerous results on the memory mechanism originated from patient studies.

Headaches, jaw discomfort, lose of eye site.