the bone in my left arm is killing me/pain when i lift my arm; the bone in my left arm is killing me/pain when i lift my arm; This is a spontaneous report received from a Consumer or other non HCP from medical information team. A female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), in 2023 as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation; fluticasone furoate, umeclidinium bromide, vilanterol trifenatate (TRELEGY); alprazolam (XANAX). The patient’s relevant medical history included: “copd” (unspecified if ongoing). The patient’s concomitant medications were not reported. Vaccination history included: Covid-19 vaccine (Dose 1; unknown manufacturer), for covid-19 immunization; Covid-19 vaccine (Dose 2; unknown manufacturer), for covid-19 immunization. The following information was reported: BONE PAIN (hospitalization, life threatening), JOINT RANGE OF MOTION DECREASED (hospitalization, life threatening), outcome “unknown” and all described as “the bone in my left arm is killing me/pain when i lift my arm”. The event “the bone in my left arm is killing me/pain when i lift my arm” required emergency room visit. The action taken for fluticasone furoate, umeclidinium bromide, vilanterol trifenatate and alprazolam was unknown. Clinical course: When asked if the adverse reaction required her to go to the emergency room, the patient said, “yes because the bone in my left arm is killing me”. Patient can feel pain in her bone and cannot lift up her arm and definitely need more than an x-ray because it would not show in the x-ray. This happens for doing the right thing, getting a booster shot for covid which she received 2 years ago (in 2023). She has pain when she lifts her arm. The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 will be requested and submitted if and when received.