flu; flu vaccination causing uncontrollable shaking; Initial information received on 13-Jan-2025 regarding an unsolicited valid serious case received from a Patient. This case is linked to case 2024SA216487 (Same Patient). This case involves elderly female patient (weight-76.36 kg) who had flu and flu vaccination causing uncontrollable shaking after receiving Influenza Vaccine. The patient’s past medical history, medical treatment(s), vaccination(s) and family history were not provided. Concomitant medications included COQ10, Omeprazole-Sodium Bicarbonate, Singulair 10 Mg Tablet, Memantine HCL 10 Mg Tablet, Levothyroxine Sodium 75 Mcg Tablet, Potassium Chloride 20 Meq Tablet Er, Lasix 40 Mg Tablet, Breo Ellipta 100-25 mcg Blst W/Dev, Lipitor 20 Mg Tablet, Atenolol 25 Mg Tablet, Albuterol Sulfate Hfa, Pradaxa 150 Mg Capsule for Product used for unknown indication. On an unknown date, the patient received a dose of suspect Influenza Vaccine produced by unknown manufacturer (unknown strength, dosage, expiry date, formulation, batch number and route) via unknown administration site for prophylactic vaccination. On an unknown date the patient developed flu (influenza) and flu vaccination causing uncontrollable shaking (tremor) (unknown latency) following the administration of Influenza Vaccine. Information on the batch number was requested corresponding to the one at time of event occurrence. Reportedly, Patient Wanted To Inquire About Taking Dupixent Dose Following Hospitalization For Flu And Flu Vaccination Causing Uncontrollable Shaking. Patient Was In The Hospital With Flu, Dose Was Missed 10-Jan-2025, Needs To Know When Ok To Take Next Dose. Reports Missing A Dose Of Her Medication Dupixent, Mentioned Being In The Hospital And Having The Flu. Patient To Hold Off On Dose Of Dupixent If Comfortable In Tolerating A Prurigo Nodularis Flare Up Until Patient Stabilizes By Advising Patient To Take Next Dose On 24-Jan-2025 (Original Due 10-Jan-2025That Was Missed). Patient Advised That She Was Recently In The Hospital That Caused Her To Miss A Dose On 10-Jan-2025. Action taken with was not applicable. It was not reported if the patient received a corrective treatment for both the events. At time of reporting, the outcome was unknown for both the events. Seriousness criteria: The patient was hospitalized for the event (influenza).; Sender’s Comments: Sanofi company comment dated 20-Jan-2025: This case involves elderly female patient (weight-76.36 kg) who had flu and flu vaccination causing uncontrollable shaking after receiving Influenza Vaccine. The time to onset was compatible with the role of vaccine. The clinical course of the event was not provided. Furthermore, information regarding condition at the time of vaccination, role of medical history, lab data excluding other predisposing etiologies would be needed for complete assessment of the case. Based upon the reported information, the role of the suspect vaccine cannot be assessed.